Afsar Ali, Ph.D., a research associate professor in the department of environmental and global health is studying cholera epidemiology and ecology in Bangladesh with funding from the National Institutes of Health. His research has focused on how V. cholerae can persist in aquatic reservoirs for decades while causing epidemics. To this context, Ali described, for the first time, a “persister” phenotype of V. cholerae that is likely to explain how V. cholerae persists in nutrient-poor and stressful aquatic environments.

Researchers at the Center for Statistics and Quantitative Infectious Diseases, co-directed by Ira Longini, Ph.D., a professor in the department of biostatistics in the College of Public Health and Health Professions and the College of Medicine, measure the ecological determinants of cholera transmission in Bangladesh. They use mathematical models to study the potential impact of vaccination and other interventions on cholera outbreaks. Learn more.